Two Extremolytes.

One Powerful Result.

New clinical data confirms the exceptional performance of combining Ectoin® natural and Glycoin® natural in a single formulation.


Together, these two Extremolytes work in synergy to protect, repair, and visibly improve skin quality.

  • Ectoin® natural helps protect the skin’s cellular barrier, forming a resilient “cellular fortress”

  • Glycoin® natural energizes skin repair processes from within, supporting regeneration and vitality

The result: fast, measurable, and long-lasting skin benefits , even after just one application.

The Outcome After a Single Application

Visible results, right when it matters most:

  • Instant anti-aging efficacy in just 15 minutes

  • Hydration benefits lasting up to 24 hours

The Study at a Glance

  • Double-blind, randomized, placebo-controlled, in vivo study

  • 0.5% Ectoin® natural + 0.5% Glycoin® natural

  • Single application design

  • Instrumental analysis:
    Visioscan® + Corneometer®

  • Measurement points: 15 minutes and 24 hours

Instant Anti-Aging: The 15-Minute Results

Within just 15 minutes after a single application, the active cream significantly outperformed placebo across all key parameters:

  • –12% surface roughness (placebo: –3%)

  • –35% scaliness (placebo: –8%)

  • +22% skin smoothness (placebo: +5%)

Takeaway: Fast, measurable texture refinement, making this combination ideal for “instant anti-aging” positioning.

Sustained Performance: 24-Hour Results

The benefits didn’t stop at 15 minutes, they continued to build over time.

After 24 hours, the combination delivered even stronger improvements vs. placebo:

  • –18% surface roughness (placebo: –5%)

  • –42% scaliness (placebo: –11%)

  • +38% skin smoothness (placebo: +8%)

Built for Claims. Designed for Comfort.

At 0.5% Ectoin® natural + 0.5% Glycoin® natural, this combination offers high claim power at low use levels, leaving formulation space for additional actives and formats.

Best suited for products targeting:

  • Dry / rough-feeling skin

  • Visible flaking / scaliness

  • Smoother-looking texture + long-lasting hydration

Works across formats:

Creams • Serums • Eye care • Leave-on masks • and more

Elevate Modern Hydration & Barrier-Care Formulations

Discover how Ectoin® natural + Glycoin® natural can power next-generation skincare with clinically proven, fast-acting, and long-lasting results.

📩 Contact us: cosmetics@bitop.de

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